Clinical Trials
From NIER
[edit] Current ongoing clinical trials in nephrology in the Netherlands
- CONTRAST Multicenter study comparing HDF with regular HD
- CIMINO Multicenter study investigating vascular access in dialysis patients
- MASTERPLAN Multicenter randomized controlled clinical trial designed to evaluate whether a multifactorial approach with the aid of nurse-practicioners reduces cardiovascular risk in patients with chronic kidney disease.
- Mechanisms of erythropoietin action in the cardiorenal syndrome Intervention study investigating the effects of erythropoietin-treatment in cardiorenal syndrome patients with combined moderate chronic renal failure and heart failure (NYHA II-III).
- NECOSAD Multicenter prospective follow-up study among end-stage renal disease (ESRD) patients new on dialysis. The aim of the study is to monitor the quality and adequacy of dialysis treatment in the Netherlands and to provide evidence for the development and testing of guidelines.
- RENINE Continously updated database with basic data on dialysis and renal transplant patients in the Netherlands.
- PREDICTIONS (PREvention of DIabetic ComplicaTIONS) European multicenter cohortstudy aimed at identifying pathophysiologically relevant genes and biomarkers correlated to the development, progression and therapy of Diabetic Nephropathy.
- PREPARE (PREdialysis PAtients REcords-study) Observational follow up study of predialysis patients with as main objectives the determination of the rate of decline of kidney function in CRI patients and the identification of the risk or progression factors influencing this decline.
- PREVEND (Prevention of Renal and Vascular End-stage Disease) Prospective, observational cohort study, focussed to assess the impact of elevated urinary albumin loss in non-diabetic subjects on future cardiovascular and renal disease.
- TEMPO study a Phase 3, Multi-center, Double blind, Placebo-controlled, Parallel-arm Trial to Determine Long-term Safety and Efficacy of Oral Tolvaptan Tablet Regimens in Adult Subjects with Autosomal Dominant Polycystic Kidney Disease.
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